Sentence examples for binding of the key from inspiring English sources

On the other hand, binding of the key downstream HR proteins Rad51 and Rad52 to these DSBs are excluded from the nucleolus.

Specifically, the possible binding of the key embryonic stem cell transcription factors (NANOG, OCT4, SOX2, E2F4) to the SNP-regions was explored.

MafB negatively regulates RANK-L-induced osteoclastogenesis by attenuating DNA binding of the key regulators NFATc1, c-Fos and Mitf (Kim et al, 2007).

The authors present a coordinated analysis of transcriptional changes and genome-wide binding of the key transcription factor EIN3 (which accumulates upon ethylene treatment and which is both necessary and sufficient for most ethylene responses) during a time course after addition of ethylene.

Initial efforts towards the development of TLR4 antagonists largely focused on structural analogues of Kdo2-lipid A which can bind competitively to the LPS binding sites of the key receptors in the pathway and antagonize LPS/TLR4-dependent signalling.

Genome-wide binding preferences of the key components of eukaryotic preinitiation complex (PIC) have been recently measured at high resolution in Saccharomyces cerevisiae by Rhee and Pugh.

To perform a comparative analysis of genome-wide binding patterns of the key regulators simultaneously expressed in HPC7 and mast cells, we generated ChIP-Seq data for CTCF, E2A, ERG, FLI1, LMO2, MEIS1, PU.1, RUNX1 and SCL in primary mast cells and also CTCF and E2A in HPC7 cells.

To test if low WIPI-1 expression in immature AML blasts might be attributed to aberrant transcriptional regulation by myeloid transcription factors, we analyzed the 5.8 kb genomic region upstream of the WIPI-1 transcriptional start site for putative binding sites of the key myeloid transcription factor PU.1 using MatInspector.

Protein binding is one of the key elements that affects biodistribution of the nanoparticles throughout the body.

Protein binding is one of the key elements affecting biodistribution, biocompatibility, and therapeutic efficacy of the NMs [ 72, 73].

The kinetics of spherical metal ion binding reveals the key molecular details of the process by which a solvated ion is engulfed by chelators [8], [9].