Sentence examples for binding of the hormone from inspiring English sources

Hormonal action requires the binding of the hormone to specific receptors (Zouboulis 2000).

Biological effects of cortisol are substantially determined by protein binding of the hormone.

During the initial steps of ABA signaling, the binding of the hormone to the receptor induces a conformational change in the latter that allows it to sequester the PP2Cs.

According to this, the activation mechanism of GPHRs can be defined by the following independent steps: binding of the hormone or an agonist stimulating antibody to the LRD of the receptor's ECD; activation of the ECD of the receptor; signal transduction from the ECD to the TMD; activation of the TMD; and activation of the G protein.

In general, binding of the hormone ligand induces a specific position of the C-terminal helix H12, which in turn allows the co-activator peptide to bind; however overexpression of the co-activator may also lead to an active nuclear receptor, despite lack of the ligand [30].

Unfortunately, because of its more transient nature, it is not possible to quantitatively measure the influence of sABs on binding of the hormone at Site2.

Estradiol binding to ERα results in dimerization and subsequent binding of the hormone-receptor complex to specific DNA palindromic sequences (estrogen response elements) to initiate gene transcription, and therefore induce the expression of growth promoting genes.

Intracellular and intranuclear actions of hormones belonging to these classes are mediated through binding of the hormones to specific receptors.

At relatively high doses, arsenic affects the amount of hormones either by disrupting hormone synthesis and metabolism or by interfering with the binding of the hormones with their receptors.

Moreover, the absence of binding of the hormones with other foetal bovine serum components related to growth rate and the survival of cultured THP-1 cells over the course of 7 days were investigated.

These targets included weight and morphology of the thyroid gland, iodide uptake by the NIS, iodide organification by thyroid peroxidase (TPO), binding of the thyroid hormone thyroxine (T4) to TTR, the metabolism of thyroid hormones by deiodinases, and the action of the biologically active thyroid hormone triiodothyronine (T3) mediated by TRs functioning as ligand-dependent transcription factors.