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Exact(49)
In this system, the binding of the first guest (1 2 saccharide/boronic acid complex) suppresses the rotational freedom of the two porphyrin planes, which facilitates the binding of the second guest.
Negative cooperativity occurs when binding of the first substrate decreases the affinity of the enzyme for other substrate molecules.
Positive cooperativity occurs when binding of the first substrate molecule increases the affinity of the other active sites for substrate.
FITC Donkey anti-Goat IgG (1.5 µg/ml, Jackson IR) was used to visualize binding of the first antibody.
A Hill coefficient "n" higher than unity is indicative of a high degree of cooperativity, meaning that the binding of the first monomer facilitates the binding of the second monomer.
Triggering activation of the usher protein involves the binding of the first chaperone-subunit complex.
Similar(11)
If the compounds bind the immobilized protein, the binding of the second protein will be reduced; otherwise, the binding will be largely retained.
Upon binding of the fourth inhibitor the dimer interface, however, becomes partially disordered.
The authors conclude a subsite binding of the second peptide unit close to the main binding pocket.
The binding of the second K+ ion also started with water dehydration at about 159 ns (Fig. 2D).
Substrate activation can result from an allosteric effect due to binding of the second substrate molecule on the PAS.
More suggestions(19)
bonding of the first
binding of the highest
binders of the first
determining of the first
obligations of the first
binding of the largest
binding of the 1st
binding of the radiolabelled
binding of the active
binding of the targeted
binding of the immunoconjugate
binding of the polyclonal
binding of the secondary
binding of the hybrid
binding of the former
binding of the different
binding of the non
binding of the same
binding of the second
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