Sentence examples for binding of the fatty from inspiring English sources

Binding of the flavonoid to MtbHadAB can physically occlude binding of the fatty acid into the substrate binding channel (Fig. 6A).

Therefore, the flavonoids can scuttle binding of the fatty acid or prevent it from binding in a catalytically competent orientation.

Although 18∶2 strikingly increased PPARγ activity in the CHO-GPAT1 cells, the observed increase in PPARγ activity in this and other studies [13] might be due either to direct binding of the fatty acid to PPARγ or to an increase in the total amount of LPA available as an agonist.

These two Arg residues are therefore unlikely to contribute to binding of the fatty acid to the nonannular sites.

Acyl-ACP crystal structures show that the hydrophobic tunnel is plastic, and binding of the fatty acyl-chain can expand the internal cavity volume to about 164 Å for decanoyl-ACP relative to apo-ACP.

The structure of fumonisin B1 13 and the characteristics of the inhibition suggest that the aminopentol backbone competes for binding of the sphingoid base substrate, whereas the anionic tricarballylic acids may interfere with binding of the fatty acyl-CoA.

In designing the synthetic derivatives, we focused on the binding position of the fatty chain.

This study clearly shows that the number and the binding position of the fatty chain are critical for protective activity against ER stress-dependent cell death.

SPEFS was used to follow the kinetics of the binding of the labeled fatty acid to the antibody, and to implement a competition assay with free fatty acid (undecanoic acid), sensitive at the 1 μM scale, a sensitivity limit caused by the low affinity of antibodies for free fatty acids, rather than the SPEFS technique itself.

To determine how the V41Y and A134F variants were able to discriminate against the binding of the native fatty acid ligands, we generated crystal structures of both V41Y and A134F in the presence of hexanoic acid.

The strength of binding of the monounsaturated fatty acids increases with an increasing chain length from myristoleic acid (C14) to ecosenoic acid (C20) but then falls again to erucic acid (C22).