Sentence examples for binding of the factors from inspiring English sources

Since the basal activity of the PADI3 core promoter required binding of the factors Sp1/3 and NF-Y [13], we mutated the CCAAT or the GC-boxes, which bind NF-Y and Sp1/3 respectively, within the PADI3 promoter sequences in reporter plasmids.

As a negative control, binding of the factors was also monitored at an irrelevant DNA region (negative control [NC] DNA).

In transcription and replication, changes in the chromatin structure are required in order to allow binding of the factors involved [ 4, 5].

As most TF binding of the factors we profiled occur outside of proximal promoters, it is likely that many more human mutations that regulate genes through long-range interactions remain to be found.

To elucidate the binding of these factors to the respective promoters, we performed chromatin immune-precipitations.

Initiation thus requires that the DNA structure facilitates the binding of these factors as well as the appropriate DNA melting.

BMP-6 treatment significantly reduced the binding of these factors to miPPR-21 by decreasing the expression of δEF1 and c-Fos/c-Jun.

The binding profiles of the factors Bcd and Kr were taken from the results of in vitro bacterial one hybrid (B1H) experiments [55].

The increase in conservation is higher than expected solely based on the combined binding sites of the factors studied.

Mutated sequences of the transcription factors were also used to check the specificity of the binding of the transcription factors.

Therefore, to reveal how the initial binding of the 'pioneer factors' changes nucleosome organizations during reprogramming requires stepwise maps of nucleosome position and binding of the 'pioneer factors'.