Sentence examples for binding of the central from inspiring English sources

The results pinpoint the outer margins of binding of the central fingers within helices IV and II of TFIIIA.

Note that synphilin-1 dimerization has been observed previously and found to involve the antiparallel binding of the central coiled-coil domain [20].

It is theoretically possible that binding of the central complexin helix to the SNARE complex is required in order to enable binding of the accessory helix of the second complexin molecule.

Consistent with a potential role in PK formation, RimP has previously been shown to accelerate binding of the central PK-associated r-proteins S5 and S12 in in vitro 30S assembly assays (Bunner et al., 2010b).

Thus, binding of the central helix to the SNARE complex places the accessory helix right between the membranes at the space where they need to be brought together for fusion, and such action is very likely to be hindered at least to some extent by steric and electrostatic repulsion between the negatively charged membranes and the accessory helix.

The inhibition is achieved by binding of the central element of Sti1, TPR2A TPR2B, to the C-terminal end of Hsp90 and the Hsp90 middle domain which leads to a stabilization of the open conformation of Hsp90 25, 26, 27, 27.

LNZ inhibits the formation of protein synthesis initiation complexes by binding to the central loop segment of domain V of the 23S rRNA [ 6].

Instead, it is proposed that the EPR studies detect binding to the central hydrophobic cavity of the channel, with a binding constant in the range of ∼0.1 1 μM.

Taken together the data indicate that a form of vps1 carrying a mutation E461K in the proposed actin binding helix of the central stalk domain is still able to bind actin.

Aspin, head of research and scholarship at the vast library of the Wellcome Collection, has just acquired the book from a London dealer for "a low five-figure sum", and is adding it to the special bindings section of the central London museum.

A key conformational change in the motor domain following Mg-ATP binding is peeling of the central β-sheet from the C-terminus of helix-α4 increasing their separation; this is required to accommodate rotation of helix-α6 and consequent neck linker docking.