Sentence examples for binding of the aptamer from inspiring English sources

Due to the binding of the aptamer by ATP, it trigger DNA polymerase and Exo III assisted target recycling process by the product of release, the complex would change into the "on" state as a result of the dissociation of the FAM from the surface of PDANSs, thus providing greatly enhanced fluorescence emission intensity.

The method utilises the fact the binding of the aptamer to the protein results in a change in charge density on the bead surface, the isoelectric point of the protein then dominates the mobility of the beads, creating a multiplexed assay termed AptaTRPS.

We therefore performed binding assays at 37°C to verify the stability of the binding of the aptamer to its target.

The binding of the aptamer to VACV was assayed by Fluorescence Correlation Spectroscopy (FCS [ 30].

The contribution of copper-containing agarose beads in binding of the aptamer pool after the eighth SELEX round was insignificant.

Further studies are therefore warranted to identify the viral mechanisms disrupted by binding of the aptamer QA-12.

The binding of this aptamer pool to the target-containing resin was merely over 600-fold higher when compared to empty resin (Fig.  1b).

The release kinetics of growth factors can be molecularly modulated by either changing the binding affinity of the aptamer or by using a triggering effector.

Aptamer beacon is a promising technique to resolve this problem by combining the excellent protein binding specificity of the aptamer with the sensitive signal transduction mechanism of the molecular beacon.

To determine if the binding affinity of the aptamer was deteriorated in the context of ASAP, the initial rates of fluorescence enhancement were calculated and plotted against the ATP concentrations (Figure 5).

Analysis of the consensus sequence identified a stem-loop structure, which might be the possible binding site of the aptamer [ 32].