Sentence examples for binding of the antibiotic from inspiring English sources

The potential peak of glutathione was shifted by binding of the antibiotic.

This interaction, along with the binding of the antibiotic to the 23S rRNA in the large subunit, also causes translocation blockade and inhibition of ribosome recycling.

TRAs may hinder binding of the antibiotic to its target or affect the regulation of the gene, causing the antibiotic to be less effective.

The Asp insertion may lower the rate of acylation by sterically impeding binding of the antibiotic or by hindering breakage of the β-lactam ring during acylation because of the negative charge of its side chain.

The structure shows that functionally the Asp insertion comes after Asp346, as the first Asp of the pair retains its interaction with Ser363, while the second Asp points directly toward the β-lactam-binding site where it interferes with binding of the antibiotic or the chemistry of acylation.

Binding of the antibiotic leads to transduction of the signal across the membrane, whereby the cytoplasmic zinc-dependent protease domain of BlaR1 or MecR1 is activated.

It should be noted that the best detection was obtained in milk with low protein content, which could be the result of decreased binding of the antibiotics to protein material.

X-ray snapshots taken 30 milliseconds to 2 seconds after the reaction began showed lactamase binding to the antibiotic, ceftriaxone, and bursting one of its chemical bonds.

Loss of A1518/A1519 methylation by inactivation of the homologous enzyme RsmA (formerly KsgA) in E. coli perturbs the binding site of the antibiotic kasugamycin (25) to confer resistance (26, 27).

The phenolic OH of Hpg4 serves as the "hot seat" for loading sugar moieties on GPAs; this reflects its relative availability for modification given its spatial separation from the acyl- d-alanyl d-alanine binding region of the antibiotic as well as the role that sugars at this position play in back-to-back dimerization.

Here, we use site-specific mutagenesis, coupled with calorimetric, NMR, and enzymological techniques, to define the key interactions that govern the binding of the aminoglycoside antibiotics neomycin and kanamycin B to APH(3′ -IIIa (an antibiotic phosphorylating enzyme that confers resistance).