Sentence examples for binding of specific targets from inspiring English sources
With increasing expression competitive binding of specific targets progressively unmasks their actual 3′/5′ gradient, until probe saturation sets in.
Conclusion: We have developed a family of nanoparticles based on degradable, biocompatible and functionalisable polymers, enabling the binding of specific targeting agents (eg. peptides) and incorporating an imaging agent, either for optical or scintigraphic imaging.
The CUE domain is a ubiquitin-binding motif, which initiates proteolytic degradation of specific targets [ 10].
Tethering the PKA regulatory subunit(R) to specific subcellular sites by binding AKAPs helps to assure specific phosphorylation of specific targets and thus prevents uncontrolled phosphorylation.
Upon physiological and environmental stimuli TFs (sequence specific DNA binding proteins) modulate transcription of specific target genes by binding to cis-elements located in gene promoters and/or introns [78] [80].
They constitute a highly suitable carrier for directing radioisotopes or toxins to HER2-positive tumor cells because of specific target binding and lack of specific non-receptor interactions, such as the Fc receptor binding displayed by some antibodies.
This structural conservation suggests that ERH in other species may use the same interface to interact with its binding partners to regulate expression of specific target genes.
Although detection strategies are different for various aptamer-based assays, the core of the design strategies is similar towards reporting the presence of specific target binding to the corresponding aptamers.
Tracers were classified as functional or non-functional based on their utility in vivo for reliable quantification of specific target binding.
They participate in Ca2+ signal transduction by binding and modifying the activities of specific target proteins.
In these instances of imperfect complementarity, there is often a short, ∼6 8 nt "seed" region, located near the 5′ end of the miRNA, which appears to be of paramount importance in terms of dictating binding to specific target mRNAs [1].
