Sentence examples for binding of specific ligands from inspiring English sources

The binding of specific ligands to the telomeric G-quadruplex is a strategy to alter telomere functions and to inhibit cell growth.

They typically act via the binding of specific ligands (e.g. purine molecules) to riboswitch regulatory elements in 5' UTR of mRNA's, thus prompting or inhibiting their translation.

Importantly, these data demonstrate that the oligomeric state of NEMO is modulated by binding of specific ligands.

EGFR is activated by binding of specific ligands, including epidermal growth factor and transforming growth factor α (TGF α).

PPARgamma belongs to the nuclear hormone receptor family of transcription factors, which are activated upon binding of specific ligands or agonists.

The binding of specific ligands leads to a structural reorganization of the cytosolic TIR domains, which is used as a signaling platform for adaptor recruitment.

Furthermore GSTs have cellular physiology roles such as regulators of cellular pathways of stress response and housekeeping roles in the binding and transport of specific ligands [28].

The ultrafiltration-based affinity MS technique has been established to search for ligands, verify binding and estimate affinity of specific ligands for given soluble protein targets (Chen et al. 2015; Qin et al. 2015).

Specific sets of variably modified disaccharides, usually within the sulfated domains, define binding sites for a multitude of specific ligands such as cytokines, chemokines, growth factors, enzymes and enzyme inhibitors, and ECM proteins [ 14, 15].

TRPV1 can be detected using RT-PCR and radioligand binding throughout the neuroaxis, and the identification of specific ligands such as NADA in certain brain regions further suggests its roles in the CNS.

Thus, it is tempting to speculate that EGFR variant may alter binding of its specific ligands leading to a particular phenotype of EGFR signaling.