Sentence examples for binding of small compounds from inspiring English sources

This effect has been found to be able to enhance the binding of small compounds and influence the capture of nucleic acids in the nanopore.

The coupling technology is applicable to many haptens and hapten binding antibodies (confirmed by automated analyses of the structures of 140 additional hapten binding antibodies) and can be applied to modulate the pharmacokinetics of small compounds or peptides.

Structure-based identification of small compound inhibitors of Aβ toxicity.

We hypothesized that backbone compliance may play a role in protein protein recognition and in the mechanism of binding of small-molecule compounds to protein surfaces.

The use of the ANS dye with the Rotor-Gene Q instrument has been demonstrated to work with our model protein to study binding of small-molecule compounds by using different levels of gain in a single PTM experiment.

We considered that a biophysical method, surface plasmon resonance, would allow the detection of direct binding of small molecules to sGC and would complement the biochemical characterisation of compounds.

Based on our previously generated insight into the binding of small molecules into Mdm2 and Mdm4 and our recently developed Mdm2 and Mdm4 fluorescence polarization assay, we planned to synthesized libraries of potential Mdm2/4 binding compounds.

Thanos et al. [43] have published the structure of the small compound SP4206 binding to an IL-2 cytokine, which in turn blocks the natural interaction of IL-2 and its receptor IL-2Rα.

This density might be due to low-occupancy binding of a small, eugenol-resembling compound that originated from bacterial growth-media derived from yeast extracts.

199, 200 Based on this strategy, Chrunyk and colleagues proposed to design small compounds to mimic the binding of antibodies that can act as blocking agents of PPI.

DNA binding of such compounds was not systematically studied yet.