Sentence examples for binding of shikimate in from inspiring English sources

The binding of shikimate in a shikimate kinase crystal structure has not previously been reported.

Crystallographic analysis of EPSP synthase from Escherichia coli, in complex with shikimate/glyphosate at 1.5 Å resolution, revealed that binding of shikimate induces changes around the backbone of the active site, which in turn impact the efficient binding of glyphosate.

This theory is supported by the increased abundance of shikimate in crown buds post foliar glyphosate-treatment and prior to growth-induction (Fig.  2).

This alignment gave a score of 149 with an e-value of 10-44, but corresponded only to the ATP-binding domain of shikimate kinase encoded on chromosome 10 (accession number NT_008705.15).

In addition, tyrosine amount decreased in kappa ox plants and the contents of shikimate increased in kappa KO plants (Table 1).

The precursor substrate phenylpyruvate is an intermediates of shikimate pathway in E. coli.

These results also fit well with the abundance of shikimate observed in the same aerial tissues (Fig.  2).

With the objective of clarifying the mechanism of Schiff base formation, we characterized the binding of quinate and shikimate to the wild-type and K170M mutant DHQD using ITC, NMR, and X-ray crystallography.

Detailed knowledge of shikimate binding is an important step in the design of inhibitors of SK, which have potential as novel anti-tuberculosis agents.

The pipeline for DHQase sequence design, chemical synthesis and purification established from this study has been generalized for other enzymes of the shikimate pathway, and construction of a catalytic part library of shikimate pathway is in progress.

However, abundance of shikimate was similar in a subsequent generation of aerial shoots derived from crown buds of treated and untreated plants, suggesting EPSPS is no longer inhibited or abundance of shikimate initially observed in crown buds dissipated over time.