Sentence examples for binding of particular nucleotides from inspiring English sources

Mallam et al. propose that present-day helicases have diversified from enzymes that had broad specificity for RNA and DNA, by optimizing interactions that favor the binding of particular nucleotides and nucleic acids.

It was noticed early that especially the 5' end of miRNAs is important for the binding of target mRNAs [ 2], in particular nucleotides 2-8, sometimes referred to as the 'seed' [ 3].

GAF domains regulate the catalytic activity of certain vertebrate cyclic nucleotide phosphodiesterases (PDEs) by allosteric, noncatalytic binding of cyclic nucleotides.

We designed a technique that directly determines binding of cyclic nucleotides to the prokaryotic cyclic nucleotide modulated ion channel MloK1.

Opening of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated by direct binding of cyclic nucleotides to a cyclic nucleotide-binding domain (CNBD) in the C-terminus.

Each of these rSNPs has previous empirical evidence to show that the nucleotide variation disrupts the binding of a particular TF.

Although a comprehensive understanding of the molecular features of the binding of this particular dye to DNA is lacking, the binding site for similar dyes is only two to four nucleotides [ 24].

The detection occurs by complementary binding of nucleotides like adenine (A) to thymine (T) and cytosine (C) to guanine (G).

Our AMP and DNA bound structures show that the binding of nucleotides to the core domain is stabilized through interactions between phosphate atoms and positively charged residues which are part of the identified binding site, in particular the side chains of Lys91 and Arg149.

Moreover, the catalytic activity may be enabled or suppressed upon binding of a nucleotide strand [16].

We analyzed the binding of its nucleotide substrates by fluorometric methods.