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These C-terminal sequences may contribute to the autoinhibition of the kinase activity, which can be counteracted by binding of other components.
This arrangement enables eIF3 components to completely encircle the 40S subunit and to engage and coordinate the binding of other components of the translation initiation machinery at both ends of the mRNA channel.
As they bind to the pre-mRNP, the hnRNP proteins can affect the structure of the pre-mRNP and the binding of other components, thereby influencing many aspects of synthesis, processing and function of pre-mRNPs/mRNPs, for example, polyadenylation, mRNA stability, export and translation.
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The constituent parts of DNA promoters, ribosome-binding sites, plasmid backbones, and thousands of other components—are catalogued, explained, and discussed.
The constituent parts of DNA — promoters, ribosome-binding sites, plasmid backbones, and thousands of other components — are catalogued, explained, and discussed.
To distinguish these possibilities, we examined whether mutations in the Edc3-binding pocket also affected the accumulation of other components in P-bodies.
Given that RIP140 is likely to be a difficult metabolic target to finely tune it would be necessary to screen for compounds that modify the recruitment of RIP140 to specific nuclear receptors at a subset of genes, or alternatively, compounds that can alter its binding to other components of the transcriptional machinery, such as histone modifying enzymes.
The majority of these ancestral fold functions promote the modern translation system through binding to other components of the translation apparatus.
For TKu, the binding buffer was modified to contain 300 mM NaCl, keeping the concentration of other components the same.
The functions of these domains in relation to cellulose degradation are not known, but possibilities include binding to cellulose, binding to other components of the cellulolytic machinery or interaction with the cell surface.
The β-TrCP family member contains a 42-48 acido acid F-box motif at the N-terminus for binding to other components of the SCF complex and seven WD40 repeats at the C-terminus for recognition of substrates, which normally contain the conserved DSGxxS motif.
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