Sentence examples for binding of multiple tetramers from inspiring English sources

However, this represents a simplified analysis of the data, because each phase presumably represents binding of multiple tetramers along the DNA.

Various methods have been used to identify activated T cells such as binding of MHC tetramers and expression of cell surface markers in addition to cytokine-based assays.

In tumor cells, deletions, mutations, methylations of p53 binding sites, or mutations of p53 such as p53mt135, disturb the binding of p53 tetramers to their binding sites, and this prevents the binding of the p300 complex to IGFBP-3 promoter.

Previous studies in humans have only demonstrated binding of HLA-G tetramers to peripheral myelomonocytic cells 38.

In any of these routes, the DCC-SSB 2·dT70 DCC-SSB 2·dT70ally, would then presumably rearrange to produce equal binding oformed tetramer.

Moreover, non-specific binding of the tetramer (as seen on the CD8-negative subset) also varied between the different laboratories.

We observed that a major naturally occurring escape variant with an amino acid substitution at position 5 (K5E) in the epitopic peptide substantially increased binding of the respective tetramer to CD14+ monocytes as compared to the tetramer refolded with the wild type tetramer (Figure 1).

Tetramer staining to dissect proper TCR formation was not possible with the 58 T-cell line due to unspecific binding of tetramer to the transferred CD8α molecule that was needed for the functional analysis of the TCRs.

Under some conditions (high SSB and/or low ionic strength), a second tetramer binds to each 70-base length, but at a rate 2 orders of magnitude slower than the rate of binding of the first tetramer.

As an example of the coupling of multiple binding sites, Eph-ephrin binding may form hetero-tetramer or higher oligomers [ 11], which can lead to tighter cell adhesion.

In addition we quantify the p53 target binding properties of tetramers and hexamers in comparison with dimer.