Sentence examples for binding of multiple VHHs from inspiring English sources

This can be accomplished either by binding of multiple VHHs to a single LT molecule or by blocking of multiple receptor sites by a single VHH.

AH cloned the VHHs fragment, evaluated the expression and binding of the VHHs and wrote the first draft of the manuscript.

The small size of the VHHs is particularly important for this application as it allows simultaneous binding of different VHHs to neighbouring molecules, most likely without steric hindrance.

In addition, non-competitive VHHs targeting the same tumour marker could be combined as simultaneous binding of different VHHs to the same target molecule would likely lead to even better T/B ratios and consequently to an improved tumour detection.

Whether the longer CDR3 loops of these antibodies penetrate inside the cavity or, alternatively, the binding of the VHHs does not allow the access of the acceptor lactose, remains to be demonstrated.

The binding of the VHH to the coating antigen T3-BSA was subsequently evaluated by ELISA.

We also provide visualization of the specificity of binding of VHH B11 to the Chlamydomonas cell surface by creating and employing VHH B11 green or red fluorescent proteins that brightly decorate the exterior of live Chlamydomonas cells, but not the surfaces of unrelated algae, during fluorescence microscopy.

We measured the binding affinity of VHHs to mutant TcTSTrp312Ala and TcTSTyr119Ser.

Stereo view of the binding site of VHH-BS1 (gray) with LAP1 (blue).

Contribution of multiple binding sites.

To avoid any detrimental effects of fluorophore conjugation on the binding capacity of the VHH, we performed the conjugation using maleimide-modified fluorophores that bind directly to the C-terminal cysteine at the VHH.