Sentence examples for binding of its hormone from inspiring English sources

18, 19 AR activation requires two major stimuli: 1) binding of its hormone ligand (androgen), and 2) derepression of its inhibitory nuclear coregulator FoxO1.

Demay M, Mitchell J, Goltzman D. Comparison of renal and osseous binding of parathyroid hormone and hormonal fragments.

They can also be treated with radiation therapy or with drugs such as pegvisomant, which blocks the binding of growth hormone to its receptors, and synthetic long-acting analogues of somatostatin, which inhibit the secretion of GH.

The LEPR gene 223A > G polymorphism is expected to have an impact on the binding of the hormone to its receptor.

The content of this database comprises information about the biological components of the endocrine system, like hormones, receptors and cells, as well as their relations like the secretion or the binding of a hormone to its receptor.

PLC is activated by binding of a hormone or growth factor to its receptor and PLC in turn converts phosphatidylinositol-4,5-bisphosphate into inositol 1,4,5-trisphosphate (IP3) and diacylglycerol.

Hormonal action requires the binding of the hormone to specific receptors (Zouboulis 2000).

Unfortunately, because of its more transient nature, it is not possible to quantitatively measure the influence of sABs on binding of the hormone at Site2.

Biological effects of cortisol are substantially determined by protein binding of the hormone.

For example, a tumor that expresses high levels of estrogen receptor, indicating it relies on estrogen to grow, might be successfully treated by drugs that block the binding of the hormone to the cancer.

Brian Kobilka, MD, professor of molecular and cellular physiology: His pioneering X-ray crystallographic studies have revealed how the binding of a hormone to the extracellular pocket on a G-protein coupled receptor is transmitted across the cell membrane to trigger a signaling cascade.