Sentence examples for binding of further factors from inspiring English sources

However, an N-terminal deletion mutant of Foxp3 was also incapable of performing these functions, suggesting that binding of further factors might be required [18].

The ENCODE data start to paint a picture of the logic and architecture of transcriptional networks, in which DNA binding of a few high-affinity transcription factors displaces nucleosomes and creates a DHS, which in turn facilitates the binding of further, lower-affinity factors.

It has been proposed that the dimer functions as a molecular chaperone by binding the secondary structures of various IRESs and inducing structural changes of the IRESs that favor further binding of other initiation factors and the small ribosome [9], [35], [36].

To further validate the binding profiles, and to examine binding of ETS factors to DNA in vivo, we used ChIP-seq to determine occupied sites for each class of ETS factors in cell lines.

Further studies are now warranted to evaluate whether hypermethylation of these sites interferes with the binding of transcription factors, and how such disruption may influence CLDN11 gene transcription.

Zaret, K. S., Lerner, J. & Iwafuchi-Doi, M. Chromatin scanning by dynamic binding of pioneer factors.

Chronis, C. et al. Cooperative binding of transcription factors orchestrates reprogramming.

Results from bioinformatics analysis further indicate that the mechanism of the rs2027432 polymorphism's affecting promoter activity might be due to its effect on the binding of transcription factor MyoD, which might be further confirmed by a electrophoretic mobility shift assay.

Further factors slow progress.

Indeed, further studies are necessary to provide experimental evidence for the binding of predicted transcription factors.

We further confirmed mass spectrum data by co-IP experiments, and observed a selective binding of TRAP1 to factors eIF4A, eEF1A and eEF1G.