Sentence examples for binding of environmental from inspiring English sources

Thus, binding of environmental ligands imposed different structural constraints on the LBDs of the two ER subtypes, which most likely account for the differential contribution of both AFs in ERα and ERβ.

The transcriptional activation of the CYP1A1 gene is mediated by the binding of environmental pollutants and inhalation chemicals, notably substrates of the CYP1A1 enzyme, to the cytosolic receptor AhR and is also mediated by its translocation to the nucleus and subsequent formation of a dimer, which interacts with the corresponding xenobiotic response elements to activate transcription [ 3].

Several different in vitro assays have described the determination of the binding potency of environmental pollutants to TTR, either based on radiolabeled ligand competitive binding (RLBA) or on the use of non-radiolabeled ligand competitive binding (BA, SPR, ANSA, and FLU-TTR).

Most toxicologic studies have focused on the competitive binding assessment of environmental contaminants with T4, without evaluating their ability to modify transport protein synthesis.

The ultimate goal of the studies on the basic chemical aspects of anion receptor design of functional pH-independent systems is to target selective binding of anions of environmental significance.

In addition to providing a better understanding of the differential activities, binding affinities, and specificities of environmental ER ligands, the structures provide rational guidelines for the design of safer chemicals.

The input and output domains of these systems display a remarkable diversity, are widely distributed across species, and are mainly involved in DNA binding and the intracellular detection of environmental stimuli [128].

M. pulcherrima is well-known for its production of the red pigment, pulcherrimin formed by irreversible binding of pulcherrimic acid and environmental iron to create a metal-organic framework.

The results stress the importance of including the influence of the random nature of environmental actions, chloride binding, convection and two-dimensional chloride ingress for a comprehensive lifetime assessment.

A variety of environmental contaminants exhibit binding affinities for GPR30 and agonist activities similar to those for ERs (Thomas and Dong 2006).

A variety of environmental contaminants exhibit binding affinities for GPR30 as well as agonist activities similar to those for ER (Thomas and Dong 2006).