Sentence examples for binding of endogenous ligands from inspiring English sources

Current evidence suggests that binding of endogenous ligands to CD22 leads to modulation of B-cell activation by antigen.

In the current studies we examined the binding of endogenous ligands, artificial ligands, and potent endocrine-disrupting chemicals to wild-type and Asp351 mutants of the human estrogen receptor-α ligand-binding domain.

In this scenario, the binding of endogenous ligands, such as CD44 on T cells, would be the primary function of LSECtin, which has been hijacked by certain pathogens such as Ebola virus.

Tan IIA can stably dock with the kinase structural domain of the binding site of endogenous ligand (Fig. 7D).

We found, after molecule docking in two ways, Tan IIA docking with the binding site of endogenous ligand is more stable.

The active site of the docking of Tan IIA and VEGFR2 (PDB ID: 3VHE) may be defined as the structural domain of the binding site of endogenous ligand, according to related references.

Compared to other nuclear receptors, PPARs have a large lipid-binding pocket capable of encompassing a range of endogenous ligands [ 34].

For example, fluxes in the levels of endogenous ligands influence the receptors that are available for binding by radioligands as well as by receptor-targeting pharmaceuticals.

Bile acids (BA) act as activating signals of endogenous ligands such as Farnesoid-X receptor (FXR).

LXR RXR, upon binding of endogenous oxysterol ligands, promotes the expression of reverse cholesterol transport genes (ApoE and ABCA1) [ 21, 42].

Although the CDR2-containing epitope does not seem to be involved in the binding of endogenous cognate ligands (CD80 and CD86) and mAb engagement would not be antagonistic, the epitope might present an allosteric site for non-competitive inhibition.