Sentence examples for binding of each motif from inspiring English sources

The binding of each motif to a Kelch domain ("two-site substrate recognition") is required for the ubiquitination of Nrf2 that leads to its rapid degradation by 26S proteasome under basal conditions.

Many simple motif extraction algorithms have been proposed primarily for extracting the transcription factor binding sites, where each motif consists of a unique binding site [ 4- 10] or two binding sites separated by a fixed number of gaps [ 11- 13].

Given the splicing index (SI) [ 19] of each differentially expressed exon and the number of binding sites for each motif candidate, SplicingModeler predicts the CAEs as well as their relative functional levels (RFL) by selecting the most significant motifs with the highest Exon Inclusion Contribution (EIC) scores.

Compared with the structure of TIS11D, the characteristic KTEL V) motif at the N-terminus of each zinc finger domain provides a critical part of the RNA-binding surface; each motif forms two walls of a deep pocket that accommodates the bases of U6 and U2 in fingers 1 and 2, respectively.

Our search identified enriched cis-regulatory sequences for FOXA1 in 31%, GATA3 in 34%, and EREs at 20% of the ZNF217 binding sites of which the density of each motif is enriched ± 200 bp relative to the center of the ZNF217 binding peak.

Here, we provide the thermodynamic and structural basis for the binding of this motif by the Src SH2 domain.

However, the binding of one RGD motif to αvβ3 will increase the "local concentration" of second RGD motif in the vicinity of αvβ3 sites (Fig. 5B).

Mechanistically, L. monocytogenes and LLO induced oligomerization of NLRX1 to promote binding of its LIR motif to LC3 for induction of mitophagy.

Fluorescence anisotropy was also used to asses the binding of the HTHi motif to IBD-LEDGF.

Many protein complexes are now known to involve the binding of linear motifs in one of the binding partners.

We reasoned that binding of such motifs may be disrupted by susceptibility-associated variation near rs11121129.