Sentence examples for binding of different substrates from inspiring English sources

The sequences also indicated the presence of conserved amino acid residues and motifs that are present in mammalian hexokinases and are involved in the binding of different substrates.

This multienzymatic activity can be explained by the flexible substrate-binding pocket in the active site, which facilitates the binding of different substrates [ 3].

(1202) Extensive photoaffinity labeling studies on binding of different substrates to PGP and single-point mutagenesis analyses, as recently reviewed, 1045) delineate the associations between structure and function.

However, ultra-affinity was implicitely suggested in a series of works assessing the binding of different substrates to Hsp70s, always in the presence of a co-localized JDP, thus ensuring maximal hydrolysis acceleration upon substrate binding (Misselwitz et al., 1998; Laufen et al., 1999; Sullivan et al., 2001).

The potential use of MHETase in recycling of these alternative polyesters underlines the need to understand and customize binding to different substrates.

These results were interpreted as evidence of a substrate-induced fit mechanism for the binding of different transport substrates by Pgp.

Studies show that GDSL hydrolases have a flexible active site that appears to change conformation with the presence and binding of the different substrates, much like the induced fit mechanism proposed by Koshland.

There is substantial evidence supporting changes of the overall chemical reaction [ 7], as well as results reporting the importance of binding different substrates in the evolution of function in superfamilies [ 8,9,10 ].

In addition, substrate-activator binding might help orient the activator to enhance the efficiency of E2 binding, and different substrates might be more or less effective in doing this.

Many enzymes have broad ranges of binding affinity for different substrates that allows them to affect a variety of cellular pathways.

Hill equation, originated from the NICA model, was proposed to describe the binding of different species onto homogeneous substrates.