Sentence examples for binding of different proteins from inspiring English sources

To conduct PCA analysis, a matrix was generated with CBP bound regions as observations and the amount of binding of different proteins in CBP bound regions as variables.

Instead, apo-NEMO forms a highly elongated coiled-coil that is poised to accommodate the binding of different proteins, apparently without major structural rearrangements.

To calculate the amount of binding of different proteins at CBP sites, the top three consecutive binding values for each protein within 150 bp of the CBP peak centre was averaged.

11 The following are the main epigenetic modifications that occur in the DNA molecule: 1) binding of different proteins to the DNA such as histones and methyl-binding proteins, 2) addition of chemical groups in the bases of the DNA such as methyl (CH3), and 3) microRNAs and other noncoding RNAs that can regulate the expression of genes through various mechanisms.

The utility of the approach is demonstrated by (i) separating known similar binding site pairs from random binding site pairs and (ii) a bioisosteric replacement study for fragments binding to subpockets of different proteins.

Like many other flexible proteins in biology, members of the SIBLING family are thought to function by binding to a number of different proteins using short motifs that remain conserved while many of the intervening amino acids are permitted to change with time.

In this superfamily, new members were all from cAMP-binding domain family but consisted of different proteins like HCN pacemaker channel (1q3e) [ 20] or transcriptional regulator (1zyb and 2gau) [ 21, 22].

We report here the first systematic comparison of ABTS-binding to different proteins, i.e. the four isoforms of Trametes versicolor, using a combination of sequence clustering, density functional theory calculations, homology modeling, and multiple induced-fit docking protocols at variable pH-dependent protonation states and T1-copper oxidation state.

The ALDHs are known to have variable conformations between non-homologous proteins just like the ligand molecules, but it is also possible that the shapes of different protein binding pockets that bind the same ligand vary [31].

These molecules have a unique molecular design in which sulfated disaccharide units are clustered in specific domains of variable length and sulfation profile, providing the chain a large array of different protein binding sites [19].

Coding constraints can potentially limit the number of different protein binding motifs of a given type in the cell, in order to avoid non-specific cross recognition.