Sentence examples for binding of certain proteins from inspiring English sources

Despite these efforts, researchers have been unable to elucidate the molecular mechanisms underlying this phenomenon, whereby genes are silenced or activated by epigenetic DNA modification or by binding of certain proteins to the donor cell genome.

Moreover, a recent study has suggested that CpG-SNPs may affect the expression of target genes by interfering with the binding of certain proteins [ 13].

Such hybrids test our minimalist design strategy: we hypothesize that we can reduce the size and structural complexity of certain proteins and still retain DNA-binding function.

Retrospective analysis of design parameters used and PMO variables revealed that active PMOs were longer, bound to their targets more strongly, had their target sites closer to the acceptor splice site of the exon, overlapped areas of open conformation (as defined by the hybridization or the RNA secondary structure prediction software), and could interfere with the binding of certain SR proteins.

Accordingly, in our previous study, the binding of certain plasma proteins (important in wound healing and inflammatory responses) to TiO2 NTs with different diameters was studied [11].

Regulation at the genome level mainly takes place during the transcription of genes into mRNA, e.g. inhibition of RNA-polymerase through the binding of certain repressor proteins [ 18].

To assess the protein interactions on the methylated PPARγ promoter region, we performed chromatin immunoprecipitation (ChIP) assays to evaluate the binding of certain MBD proteins to the PPARγ promoter.

Thus, it appears that the 5'-residue G in the consensus GTTGAC(C/T) motif and 3'-residues TC in the TTGACCTC motif may be related to specific or high-affinity binding of certain WRKY protein(s) to the promoters of OsWRKY13-influenced genes.

Without antibody recognition, this proprietary reagent could interfere with the TFs by nonspecific binding of certain DNA binding proteins.

One important aspect of this role, crucial to understanding gene regulation [ 46], is the location of the preferred binding sites for certain proteins (transcription factor binding sites or TFBSs).

In Western-blotting experiments we could detect several distinct bands in protein extracts from the wild type but not in the microcystin-deficient mutants ΔmcyB and Δmcy H(Fig. 2A) suggesting specific binding of microcystin to certain proteins.