Sentence examples for binding of cellular factors from inspiring English sources
This modification could also block the binding of cellular factors that recognize the 5′ hydroxyl group.
What is the contribution of cellular factors?
This could be due to binding of additional cellular factors to the RISCs, thus restricting the structural flexibility of the assembled protein complex.
The functions of E4 ORF 6/7 peptides of Ad7 are unknown, but the corresponding protein of adenovirus type 5 has the ability to induce the binding of cellular transcription factor E2F to the viral E2a promoter region (26).
Expression of the constitutively active FH1-FH2 fragment of DAAM1 induces inappropriate actin polymerization and microtubule stabilization, which inhibits endothelial cell growth [25]; the authors also note that the N-terminus appears to behave as a dominant inhibitory construct indicating it competes for binding of some cellular factor(s) as suggested by our findings.
The control of the expression of the early ORFs in PVs depends on the binding of cellular and viral transcription factors to the upstream regulatory region (URR) of the virus.
The structure of synaptophysin suggests that the protein may function as a channel in the synaptic vesicle membrane, with the carboxyl terminus serving as a binding site for cellular factors.
Specifically, CDSN is up-regulated in psoriatic lesisons [ 40] and one psoriasis-associated allele (rs1062470, variant 5 in Figure 6A) affects the binding of an unknown cellular factor, resulting in increased transcript stability [ 40].
Additionally, NS1 protein inhibits the processing of cellular mRNA in the nucleus by binding with the cellular factor CPSF30 and PABPII that are involved in transcriptional termination and polyadenylation (Chen et al., 1999; Nemeroff et al., 1998).
This sensitive in vivo system allows the testing of different proteins for molybdate binding under in vivo conditions and will facilitate the identification of other cellular factors needed for molybdate binding.
Next we wanted to exploit the methodology to assess the binding of HIV-1 accessory proteins engaged in a variety of interactions with cellular factors [21].
