Sentence examples for binding of both compounds from inspiring English sources

Isothermal titration calorimetry data indicated that binding of both compounds to MtOPRT have negative enthalpy and favorable Gibbs free energy probably due to their high complementarity to the enzyme's binding pocket.

In this orientation, A2062 stacks between quinupristin and the macrocyclic ring of dalfopristin, such that any modification will severely affect the binding of both compounds.

The synergistic inhibition appears to be a direct consequence of interactions between the two streptogramin components, but the fixation of A2062 in an orientation permitting simultaneous binding of both compounds contributes significantly to the synergistic activity.

In addition to the hydrogen bonding interactions between these compounds and INMT, however, rabINMT contains a glutamine at position 28 that is likely to form π-stacking interactions with the indole ring of both DMT and PDAT to contribute to the binding of both compounds for rabINMT.

To test of the generality of the F-method, we screened other inhibitors, that is, thiol-containing benzoic acids thiosalicylic acid (1) and 3,5-bis mercaptomethyl benzoic acid (2), which are reported to be relatively broad-spectrum MBL inhibitors.[ 19] Unlike the captopril isomers, upon binding of both compound 1 and 2 two new peaks were observed in the F NMR spectra.

In this study, we set out to elucidate the binding site of both compounds within the CXCR3 structure.

The least amount of binding of compounds with the membrane ergosterol was observed for this strain, whereas the increase in cell density of CA04 resulted in increased binding of both the test compounds with the ergosterol.

The least amount of binding was observed for this strain, whereas the increasing cell density of CA04 showed increased binding of both the test compounds.

Fluorescence study indicates strong binding of these compounds with both BSA and HSA.

The SPR assay was developed to provide a fast means of assaying intrinsic binding of compounds to both the full length human recombinant enzyme and a construct of the catalytic domain only (sGCcat).

Osteoblasts express both receptor types and can be influenced by selective binding of oestrogenic compounds (Onoe et al., 1997; Valachovicova et al., 2004).