Sentence examples for binding of arm from inspiring English sources

We find that the molecular basis for this effect arises through Mad/dTcf complex formation, which can inhibit the binding of Arm with dTcf and block Wg-dependent gene expression in vitro.

Our in vivo genetic analyses and target gene studies support a mechanism consistent with the in vitro binding and competition studies, namely that BMP pathway components can repress Wg target gene expression by influencing the binding of Arm and dTcf.

Further, proper polarity signaling is abolished if specific phosphorylation sites within the α-catenin binding domain of Arm are mutated.

Some prisoners writhe in discomfort at the tight binding of their arms, which are tied with the long black silk of their Taliban-style turbans.

PEGylated graphene oxide (GO) composite was successfully fabricated by chemical binding of 4-arm-PEG-NH2 and GO and applied to the immobilization of cellulase.

In the absence of acetamiprid, complementary bindings of two arm segments of the aptamers with the loop sequence of STP enforce the formation of THMS with the "open" configuration of STP, and the fluorescence of THMS is on.

Drosophila Importin-α2 is a 522 amino acid protein encoded by the gene pendulin [21] and comprises an N-terminal Importin-β binding domain and a series of ARM repeats followed by a SAR domain (Figure 1A) [38], [38].

In the presence of excess CHIP, Hsp90-dependent binding of CHIP to the ARM domain of LRRK2 can also destabilize LRRK2.

This is because binding of the N-terminal arm of cTnI is required to stabilize the "open" conformation of cNTnC [ 14, 27, 42].

Specific to the heart, the "open" conformation is stabilized by binding of the N-terminal arm of cTnI (residues 16 29) to cNTnC [ 42].

Studies with isolated proteins indicate that the mutation interferes with binding of the N-terminal arm of cTnI to cNTnC, which in effect would mimic the modulatory effect of cTnI phosphorylation at Ser23/24 on Ca2+ activation [ 4, 13, 35].