Sentence examples for binding of an unknown from inspiring English sources

This function could be due to the binding of an unknown transcription factor, a hairpin spatial structure preventing nucleosome occupancy, or both.

Specifically, CDSN is up-regulated in psoriatic lesisons [ 40] and one psoriasis-associated allele (rs1062470, variant 5 in Figure 6A) affects the binding of an unknown cellular factor, resulting in increased transcript stability [ 40].

This sequence is therefore thought to represent either an alternative DAF-16 binding site or the binding site of an unknown gene that acts in combination with DAF-16 [ 12].

The selective localization in the prometaphase stage confirmed in four different cell lines strongly suggest the possibility of a functional binding to an unknown protein.

Since the order of response currents at the same concentration of each drug reflected their binding constants, it was shown that binding capacity of an unknown drug candidate could be estimated by comparison of response currents between the leader drug and the unknown drug candidate.

Identifying the binding partners of an unknown protein may shed light into its potential biological function.

These interesting results indicate that, while both the cage and non-cage residues are involved in binding of K9-methylated histone H3, the non-cage portion of the surface has a distinct function, which presumably involves binding of a yet unknown protein that mediates the role of G9a in de novo DNA methylation of the Oct3/4 promoter.

One likely explanation for these findings is that the determining feature of binding is an unknown substructure(s) of amylose and amylopectin, and starch "fingerprint -amylopectin chains, fingerprint -amylopectinpositioned branchainsnts.

Additionally, a single nucleotide polymorphism at nucleotide-1562 in the MMP-9 gene promoter results from the substitution of cytosine (C) with thymine (T), which increases promoter activity due to the loss of the binding site for an unknown transcription repressor [ 23].

Since calpains, a group of calcium activated proteases, play a key role in GAD65/67 cleavage under excitotoxic conditions the results suggest that GADs are cleaved after ubiquitination and degradation of an unknown binding partner by the proteasome.

Whether it is through association of an unknown binding partner that regulates these events via the C-terminal hairpin or the actin-induced vinculin dimer, the contribution to cell spreading and cellular reinforcement appears to be phosphorylation dependent.