Sentence examples for binding of an additional from inspiring English sources

It has been suggested that binding of an additional, not yet identified protein may be necessary to recapitulate the observed activation in a fully pure system [47].

This system includes two reactions: a unidirectional scanning reaction in which a 40S subunit moves forward by 1 nucleotide, and binding of an additional factor.

A first binding phase in which one chitin molecule was bound with ultra-high affinity (kd = 280 pM; n = 0.99) occurred, followed by binding of an additional molecule with lower affinity (kd = 1.70 µM; n = 1.03).

Increasing the length of the flanking DNA to 18 bp from one side did not affect the affinity or the stoichiometry of ISWI binding, while further increasing the length to 71 bp provides an additional binding site leading to the binding of an additional ISWI.

Notably, the C allele of rs5743836 exhibits greater NF- κB-binding affinity because of an additional NF- κB transcriptional binding site that may lead to increased production of proinflammatory cytokines.

Various ADAMTS expression has been shown to decrease as a result of HA-CD44 binding, providing an additional mode of chondroprotection for IA-HA treatment [ 36, 38, 43].

In this study, we suggest that disruption of HP1α binding is an additional mechanism to explain the synergy seen in the combination of decitabine with carboplatin.

The time course of HNE binding to LDL is shown in Figure 3. Binding of HNE to LDL occurs in two phases: an initial "rapid phase" corresponding to more than 80% of total HNE binding within 3 h (about 70% of total binding HNE occurs in the first hour) and a "slower second phase" corresponding to about 20% of total binding during an additional 45 h.

In contrast, genes involved in more complex regulatory processes such as embryonic development have evolved longer UTRs with many microRNA target sites and perhaps also binding sites for RNA binding proteins, providing an additional layer of regulation.

Tissue-specific TF binding represents an additional attribute of active enhancers, and it is logical to postulate that such TFs facilitate recruitment of histone-modifying enzymes.

For Locus 3, the model predictions did not agree with the experimental data regardless of the choice of binding intensities, unless an additional assumption on the locus structure was made, which received, however, further support (ref. to Discussion).