Sentence examples for binding of additional cofactors from inspiring English sources

In some cases, the activation of receptors requires the binding of additional cofactors, thus adding complexity to the signaling networks.

The determinants of this transient binding activity are unclear, and could involve the recruitment of additional cofactors that release Snail-1 from its binding site, or alternatively the Snail-1-induced chromatin changes could themselves reduce binding by Snail-1.

One class of additional cofactors comprises targeting factors that recruit p97 to a specific subcellular location.

PA effectors can also be targeted to specific membranes through cooperative binding of the lipid with additional cofactors, such as membrane-anchored proteins or other lipids [ 1, 23].

However, conserved STAT binding sites in the Agrp promoter region do not function as simple repressor elements and, paradoxically, are required for fasting induced stimulation of Agrp transcription [9], suggesting a more complex mechanism of regulation involving additional cofactors.

Dynamic binding events that require the fewest additional cofactors are the ones most likely to be functional.

This might indicate the requirement for additional cofactors or phosphorylation of WRKY53 for binding to the W-boxes in the chitinase-2 promoter to occur (Wan et al. 2004; Mao et al. 2011).

Second, the model could allow the introduction of an additional cofactor related death rate.

Many proteins in nature necessitate the binding of specific cofactors to perform their biological function.

The binding of H4B cofactors was detected by the initial difference Fourier maps calculated with REFMAC.

Characteristic changes were observed in the spectra of the heme-bound ligands upon binding of the cofactors.