Sentence examples for binding of a target from inspiring English sources

The binding of a target molecule is presumed to exert an effective local perturbation in the wire.

In some cases, binding of a target molecule or ligand drives disordered folding to a more ordered state [52].

In a first step one screens for mutations that affect binding of a target protein to its partners (B).

The most interesting aspect of adapting aptamers to act as biosensors or molecular probes is their structural flexibility, which means that binding of a target usually results in structural alteration or rearrangement of the aptamer [ 115, 116].

Upon binding of a target molecule, the proximity of the probes is disrupted, rendering the device fluorescent.[ 2, 3] Aptamer beacons have been generated via one of two general strategies.

Pilot-scale studies are usually carried out to determine the binding of a target protein to a resin of interest and to determine the effect of different ionic concentrations and pH before scaling-up.

The rationale for combining two ligands was to counter weak binding of an activity element with stronger binding of a targeting element and to take advantage of a two-dimensional cell surface with both receptors embedded.

An improvement in binding to a target of interest can potentially translate into improved performance of the probe in various applications.

If the radiolabeled metabolites penetrate into the brain, signals of specific binding to a target receptor may be obscured by non-specific binding signals and hidden by background signal.

In most cases, the net effect of miRISC binding to a target mRNA is a decrease in its protein levels.

When binding to a target protein, one of the preexisting quaternary states is selected and stabilized.