Sentence examples for binding of a substrate from inspiring English sources

Figure 8: Mechanisms of enzymatic action (see text). Figure 9: Curves representing enzyme action (see text). Figure 10: Induced-fit binding of a substrate to an enzyme surface and allosteric effects (see text).

It is based on the idea that protein function is intimately related to the recognition and subsequent response to the binding of a substrate or an endogenous ligand in a well-characterized binding pocket.

This is the basis of the so-called induced-fit theory, which states that the binding of a substrate or some other molecule to an enzyme causes a change in the shape of the enzyme so as to enhance or inhibit its activity.

Host-guest chemistry is based on the reaction of binding of a substrate molecule (guest) to a receptor molecule (host) [62].

Such changes are often induced by the binding of a substrate molecule to an enzyme's active site, or the physical region of the protein that participates in chemical catalysis.

This might ensure a very rapid initiation of proteolysis after binding of a substrate.

This is not expected from the QSSA analysis of the basic PDC, and it is a consequence of efficient phosphatase binding to a substrate.

DOI: http://dx.doi.org/10.7554/eLife.00710.012 While our observation that TRiC can bind substrates via its apical domains is consistent with the current understanding of TRiC substrate interactions, our data is unprecedented in demonstrating the direct binding of fibrils (a substrate too large to be internalized).

Pietrucci et al. [13] studied the binding mechanism of a substrate using MD simulations with a so-called bias-exchange metadynamics technique.

Substrate activation of BuChE may be mediated by the binding of a second substrate molecule to a P-site that triggers a conformational change extending to the region near the catalytic triad in the active site.

The result is that the binding of a second substrate molecule to the second subunit of the enzyme differs in strength or velocity from that of the first, the third from the second, and so on.