Sentence examples for binding of a small from inspiring English sources

Second, the synonymous mutations could prevent binding of a small RNA (sRNA) targeting the gtsB transcript for degradation27.

We have also demonstrated the ability of SHAPE/FAST to detect the binding of a small molecule inhibitor to the HCV internal ribosomal entry site (IRES).

Riboswitches are domains in messenger RNAs that regulate gene expression in response to the specific binding of a small molecule.

Here off-target binding implies the binding of a small molecule of therapeutic interest to a protein target other than the primary target for which it was intended.

The RSC nucleosome remodeler acts through the motifs to establish stable +1 and −1 nucleosome positions, while binding of a small set of general regulatory (pioneer) factors at fragile nucleosome promoters plays a key role in their destabilization.

Allosteric modulation of the function of a protein occurs when the regulatory trigger, such as the binding of a small effector or inhibitor molecule, takes place some distance from the protein's active site.

A change in T m upon binding of a small-molecule ligand to target protein enables this technique to be extended for high-throughput screening and characterization of binding (Pantoliano et al. 2001; Matulis et al. 2005).

These hybrid probes include small molecules with targeting groups that interact with specific enzymes and genetically encoded proteins whose signal output is modulated by binding of a small-molecule fluorophore.

Finally, it is worth noting that dimeric AaSelA is not catalytically active, as the tRNASec is bound by two dimers and processed by the active site of the neighboring dimers (Itoh et al. 2013); however, direct binding of a smaller substrate directly to the SelA active site would eliminate the need of the pentagonal ring structure for catalysis.

The antibiotic gentamicin, which inhibits protein translation by binding to a small subunit of bacterial ribosomes and not to eukaryotic ribosomes, did not affect cluster formation efficiency.

Immunohistochemistry for fibrinogen revealed, in naïve and immune challenged colonies alike, specific antibody binding to a small population of Botryllus compartment cells.