Sentence examples for binding of a peptide from inspiring English sources

The binding of a peptide aldehyde inhibitor marks the active site in the central cavity at the amino termini of the beta subunits and suggests a novel proteolytic mechanism.

The Janus Immunogenicity Score (JIS) was recently developed to assess the likelihood of T cell recognition of an antigen, using an analysis that considers both binding of a peptide within the antigen by major histocompatability complex (MHC) and recognition of the peptide:MHC complex by cognate T cell receptor (TCR).

A fundamental requisite for favorable binding of a peptide to the surface is that the torsion angles of the peptide in the bound conformation should not be forced to have energetically unfavorable φ−ψ torsion angle values.

We have demonstrated the first wide-field fluorescence binding of a peptide in vivo, showing the advancement and feasibility of targeted detection of diseased tissue based on tissue biology rather than anatomical changes in vivo.

The binding of a peptide to the MHCII involves interactions between peptide side chains and pockets lining the MHCII peptide binding groove as well as a conserved, extensive hydrogen bond (H-bond) network between the peptide backbone and the MHCII [1].

We frequently observed that the extension or contraction by a single amino was not detrimental to HLA binding of a peptide, yet only optimal epitopes were recognized by their corresponding TCRs.

Both, the free peptide or its OVA conjugate, elicited predominantly IgG Abs that in the course of immunization were increasingly more capable of binding to a peptide conformation resembling the shape of the surface area on the native BoNT/A.

In a first in silico test, we show that by simultaneously optimizing the sequence and structure of three to nine residue peptide extensions starting from short (1 6 residue) peptide stubs in the binding pocket of a peptide binding protein, the approach can recover both the conformations and the sequences of known binding peptides.

To further explore the H-region of DmsAL in the binding of DmsD, a peptide mixture of DmsAL15 33 and DmsAL34 45 was assayed for binding.

IgG binding to a peptide analogue of the second extracellular β1AR loop (Pep 2) was quantified by ELISA following published procedures.

Binding affinities were classified as strong when the binding of a reporter peptide was inhibited by 75 100%, related to the inhibition of reporter peptide binding by a positive control peptide or as intermediate when the inhibition was 50 75%.