Your English writing platform
Discover LudwigSuggestions(5)
Exact(1)
The L107F mutation also abolished binding of a non-neutralizing MAb, 3D9, whose epitope had not been previously identified.
Similar(59)
The inability to induce robust protective immunity has been postulated to be associated with the presence of a non-neutralizing decoy epitope and heavy glycosylation in close to its neutralizing epitope.
However, inhibition of RV replication by a non-neutralizing RV VP6-specific IgA has been described [ 9].
We identified several "enabling pairs" of neutralizing and non-neutralizing anti-ebolavirus monoclonal antibodies, whose combination exhibited new functional profiles, including transforming a non-neutralizing antibody to a neutralizer.
Since the N-terminus of VP1 is reported to not contain receptor binding sites for RV, these antibodies may be directed mainly against a non-neutralizing epitope and therefore may not protect against rhinovirus infections.
The epitope cluster was mapped at the C-terminus of the spike protein; it consists of structurally intertwined epitopes recognized by two neutralizing monoclonal antibodies (mAbs), 341C and 540C, and a non-neutralizing mAb, 240C.
It may be caused by poor binding of non-neutralizing antibodies and delivery into the wrong compartment of white blood cells that have ingested the virus for destruction.
This is likely caused in part by antibody-dependent enhancement of infection of virus into monocyte/macrophage cells via Fcγ receptors, facilitated by the binding of non-neutralizing antibodies to virus.
28 PRNT measures antibodies against neutralizing epitopes, whereas ELISA measures binding antibody against non-neutralizing and neutralizing epitopes.
In fact, the recent vaccine trial in Thailand shows preliminary data indicative of protective effects from binding but non-neutralizing antibodies [82].
These data provide evidence that the EGF-P-Ad5 is protected from binding of both neutralizing and non-neutralizing antibodies.
More suggestions(3)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com