Sentence examples for binding of a new from inspiring English sources

Exact(6)

While deactivation occurs by regulated hydrolysis of the GTP phosphodiester bond, activation requires dissociation of the resulting GDP molecule, followed by binding of a new GTP.

This manuscript describes the binding of a new class of nuclear export signals (here Rio2 and CPEB4) to exporter CRM1.

This results in the generation of a peptide-free (and hence very unstable) MHC molecule that can be rescued by the binding of a new peptide ligand.

However, the tags may obscure binding of a new protein to its interacting partners, affect protein expression levels, and not be sufficiently exposed to the affinity beads, thus skewing the results.

At that point, a new FPP molecule binds, while the farnesylated protein remains bound, followed by product dissociation either prior to or concerted with binding of a new CaaX-box substrate protein.

This concept is supported by the findings from various studies of abacavir-mediated drug hypersensitivity that the binding of abacavir to the antigen-binding cleft of HLA-B∗5701 HLA-B∗5701 hindered the binding of the original repertoire of peptidesterically prompting thinderedng of a new reperthere of peptides binding immunofenic neoepithees [ 80– 82].

Similar(54)

Gone are the days when many people could save money by putting their old bindings on a new pair of skis.

After duplication of the ancestral SR, three mutations in one copy radically weakened binding to the ancestral estrogen response element (ERE) and improved binding to a new set of DNA sequences (steroid response elements, SREs).

In the case of NDUFAF1, a chaperone not found associated with mature complex I, PGZ induced its binding to a new complex of 600 kDa, likely the subcomplex B formed after fragmentation of complex I.

The crystal structure was refined up to 1.9 Å resolution, and it helps to clarify the structural features of the binding mode of a new class of chemokine binding proteins.

Comparison with a known pharmacophore model and the binding affinity of a new rigid H3 antagonist (compound 1, pKi = 8.02) allowed the characterization of a binding scheme which could also account for the different affinities observed in a recently reported series of potent H3 antagonists, characterized by a 2-aminobenzimidazole moiety.

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