Your English writing platform
Discover LudwigSuggestions(5)
Exact(6)
While deactivation occurs by regulated hydrolysis of the GTP phosphodiester bond, activation requires dissociation of the resulting GDP molecule, followed by binding of a new GTP.
This manuscript describes the binding of a new class of nuclear export signals (here Rio2 and CPEB4) to exporter CRM1.
This results in the generation of a peptide-free (and hence very unstable) MHC molecule that can be rescued by the binding of a new peptide ligand.
However, the tags may obscure binding of a new protein to its interacting partners, affect protein expression levels, and not be sufficiently exposed to the affinity beads, thus skewing the results.
At that point, a new FPP molecule binds, while the farnesylated protein remains bound, followed by product dissociation either prior to or concerted with binding of a new CaaX-box substrate protein.
This concept is supported by the findings from various studies of abacavir-mediated drug hypersensitivity that the binding of abacavir to the antigen-binding cleft of HLA-B∗5701 HLA-B∗5701 hindered the binding of the original repertoire of peptidesterically prompting thinderedng of a new reperthere of peptides binding immunofenic neoepithees [ 80– 82].
Similar(54)
Gone are the days when many people could save money by putting their old bindings on a new pair of skis.
After duplication of the ancestral SR, three mutations in one copy radically weakened binding to the ancestral estrogen response element (ERE) and improved binding to a new set of DNA sequences (steroid response elements, SREs).
In the case of NDUFAF1, a chaperone not found associated with mature complex I, PGZ induced its binding to a new complex of 600 kDa, likely the subcomplex B formed after fragmentation of complex I.
The crystal structure was refined up to 1.9 Å resolution, and it helps to clarify the structural features of the binding mode of a new class of chemokine binding proteins.
Comparison with a known pharmacophore model and the binding affinity of a new rigid H3 antagonist (compound 1, pKi = 8.02) allowed the characterization of a binding scheme which could also account for the different affinities observed in a recently reported series of potent H3 antagonists, characterized by a 2-aminobenzimidazole moiety.
More suggestions(15)
binding of a [4Fe-4S]
binding of a small
binding of a few
binding of a multimeric
binding of a molecular
binding of a monomeric
binding of a basic
binding of a ferrocene
binding of a certain
binding of a second
binding of a biotinylated-BH4-BCL2
binding of a non-neutralizing
binding of a rigid
binding of a specific
binding of a PPARα-RXRα
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com