Sentence examples for binding of a minor from inspiring English sources

For the case of the nitroalkene tail group, strong binding of a minor groove binder containing this tail group was demonstrated by both DNA footprinting and melting temperature measurements, showing a correlation between DNA binding and antibacterial activity.

However, changes of approximately 0.5 ppm for base protons in the major groove upon binding of a minor-groove ligand have been observed earlier and are probably due to conformational changes of the DNA.

Int values were 8.7 kJ/mol in the case of HL intercalation into DNA, 6.3 kJ/mol in the case of its binding with a major DNA groove, and 3.6 kJ/mol in the case of its binding with a minor DNA groove.

The obtained results showed that the intended process for metals removal, which was precipitation of metal sulfides, was responsible for binding only a minor fraction of metals.

These data showed that HL binding with a minor groove of DNA was the most stable.

In the case of C60+HL version, the binding with a minor DNA groove (Fig. 4d) occurred via CGC-GCC nucleotides.

In the presence of phosphate buffer, the effect of l-Trp on the absorption spectra of RB was practically similar to that shown in Fig. 2a, and to the RB spectra obtained in aqueous solution (Linden and Neckers 1988), indicating that the salinity of the medium does not appreciably affect the binding, pointing to a minor importance of electrostatic interactions.

The constitutive SrtA catalyzes the covalent binding of the minor ancillary AP2 to peptidoglycan and since its inactivation leads to pilus secretion [28], the 515 ΔsrtA mutant is incapable of forming biofilms according to data obtained in GBS NEM316 ΔsrtA mutant strain (Figure 6B and [9]).

Herein we demonstrate the viability of this temporary allyl-carbamate protecting approach for controlling the DNA binding of representative minor groove binders, such as bisbenzamidines, (3 and 4, Fig. 1), and of classic intercalators, like ethidium bromide (5, Fig. 1).

The results of our microarray experiments and associated sequence analysis provide insight into the sequence patterns required for binding of the minor groove binder berenil in the environment of yeast cells.

Recently, the implementation of a minor groove binding protein (MGB) and nonfluorescent quencher (NFQ) significantly improved the chemistry of the real-time PCR [ 23].