Sentence examples for binding of a lead from inspiring English sources

Then the binding of a lead ion on the first strand causes the substrate to break.

Understanding the thermodynamics of binding of a lead compound to a receptor can provide valuable information for drug design.

The binding of a miRNA leads to the degradation of the mRNA molecule or alternatively, to the suppression of mRNA translation, depending on the level of complementary binding 7. Because one miRNA can have multiple targets and one mRNA molecule can be targeted by many miRNAs, miRNAs form a complex level of regulation of gene expression.

The A aminoacyl -site close to the 3′-end of 16S rRNA aminoacyl -sitetant in the decloseg process such toatheinding of an aminoglycoside leads to erroneous protein synthesis and bacterial death.

In some cases, the binding of a ligand can lead to major conformational changes, resulting in significant different protein conformations.

VAMMPIRE-LORD (lead optimization by rational design) describes an innovative strategy to improve the binding affinity of a defined lead compound using 3D-MMPs [5].

The favourable entropic component of binding of the lead series may reflect a disordered binding mode and may explain the difficulties in obtaining a crystal structure in complex with the protein.

Displacement of 12 from the vesicle surface due to preferential binding of a modified Zn-BDPA compound leads to disruption of the FRET and a diagnostic ratiometric change in fluorescence emission, as shown in Figure 2C.

In structure-based drug design, accurate crystal structure determination of protein ligand complexes is of utmost importance in order to elucidate the binding characteristics of a putative lead to a given target.

The mode of binding of the lead molecules to the RNA target was characterized by H NMR spectroscopy.

The asymmetric binding of SecB/proOmpA led to a change in the interface between the two SecA protomers, which may cause a change in the biochemical properties of SecA.