Sentence examples for binding motifs are often from inspiring English sources
The same or similar TF binding motifs are often present in the promoters of co-regulated genes.
Furthermore, in higher eukaryotes, genes are typically regulated by combinations of TFs, and TF binding motifs are often organized into modular units [ 10].
Although these methods have been very successful for bacterial and yeast genomes, their success was limited in higher eukaryotes for which TF binding motifs are often degenerate and the search space is considerably larger.
First, binding motifs are typically short and weak (Andreatta et al., 2012), second, experimental origin of the data imposes the possibility of fair level of noise and most remarkably, multiple binding motifs are often contained within the data.
Because transposases are frequently toxic and insoluble when overexpressed, we exploited the fact that β-binding motifs are often located on highly flexible, peptide-like, structures at the C-terminus of the protein (Dalrymple et al. 2001; Bunting et al. 2003; López de Saro et al. 2003).
PHR1 is a key transcriptional activator in controlling Pi uptake and allocation, and the PHR1 binding motif is often found in the upstream regions of Arabidopsis genes induced by Pi-starvation [ 52].
The binding site motifs are often highly degenerate, which makes it challenging to build reliable models for these DNA-encoded signals [ 4].
HRE's are characterised by a RCGTG binding motif, functional motifs are often found in the promoters of hypoxia response genes but have also been seen to act distally [ 33].
Such helix-turn-helix motifs are often found on DNA binding proteins such as transcription factors, a class of proteins which are rare in trypanosomatids.
The fact that both motifs are often found in the same binding site lead us to examine the relationship of the two motifs.
