Sentence examples for binding motifs are defined from inspiring English sources

Since zinc binding motifs are defined by coordinating residue type and position but typically not by specifics in connecting sequence, they can be difficult to define by algorithm.

In case of BsuL-CTD, the metal binding motif is defined by the stretch DQHAAQERIKYEY extending from residues.

In RNAMotifModeler, the consensus of each binding motif is defined by the following components: 1) The reference motif, a k-base RNA sequence on which the protein preferably binds; 2) Retained binding affinity despite of a one-nucleotide deviation from reference motif to the sequence of one binding sites.

While the optimal mode I and II 14-3-3-binding motifs were defined using phosphopeptides [ 18, 19], target sites in proteins must satisfy the specificity requirements for both 14-3-3s 14-3-3s 14-3-3s kinands thet create the sites in the first protein

TCF/Lef and VDR variant consensus motifs were defined by comparing the natural binding sites in the promoter region of several target genes (Table S2).

The PAM2 motif is defined as an interaction interface of the MLLE domain of the poly(A -binding protein (A -bindingnd Lengauer, 2004).

The sequence features of the binding motifs are consistent with the experimentally defined cis-acting elements recognized by SRSF1 [ 5, 14, 15].

The ion binding motifs are shown.

In Fig. 1D the different binding motifs are illustrated.

Typically, the HSP72 binding motif can be defined by a linear sequence of 7 amino acids containing hydrophobic side groups or aromatic rings (1).

Taken together, these results indicate that the ETS DNA-binding specificities fall into four clearly distinct classes, and that the molecular mechanisms of the differences in four kinds of ETS-binding motifs are due to amino-acid divergences at defined DNA-contacting residues (marked 5, 9, 11 and 14 in Figure 4A).