Sentence examples for binding motif within a from inspiring English sources

Experimental evidence typically included the presence of a consensus binding motif within a core promoter, in vitro binding assays and luciferase reporter assays.

Thus, evidently the conserved residues represent a binding motif within a linker between (Pfam) structured domains or in a disordered tail at the carboxy or amino terminus of a (Pfam) structured domain [ 99].

Excluding ChIP-seq peaks that did not correspond to any of these three CTCF binding motifs, we assigned each of the 9822 genes annotated by ENSEMBLE into a group corresponding to its nearest CTCF binding motif within a [−50kbp,+50kbp] region of its TSS, or, if none, as 'other genes'.

Although the ring topology of these compounds is quite different from other lipid II binding lantibiotics, these peptides appear to contain the mersacidin-like lipid II binding motif within their A-ring.

To find out the transcription factor partners of HIPPI we carried out enrichment analysis for TF binding motifs within a fixed 100 bp distance from HBS.

The number of the identified YY1 binding motifs within a given DNA sequence corresponding to the transcript was further divided by the size of the mRNA sequence, yielding a YY1 density score.

We found 9 out of 19 genes searched had conserved Foxa2 binding motifs within a 10 kb upstream and 5 kb downstream region around the transcriptional start site (Additional File 10).

The identification of an Oct2 binding motif within unique PU.1 regions implies a potential co-activator role, as PU.1 and Oct2 have previously been shown to bind concomitantly at the Vκ19 promoter in B lymphocytes, and point mutations in the binding sites for either factor can lead to diminished immunoglobulin production [ 43].

To date, based on the identification of a Gli binding motif within their regulatory sequences, no more than a dozen target genes have been characterized to be activated or inhibited by Gli activity in vertebrates.

Consequently, in SI tissue, but not in IPI-2I or SJPL cells, Cdx-2 can bind to the putative binding motif within the TATA box of CCL25 promoter and consequently induce its expression.

We have identified a binding motif within Cap-H2 that is essential for its interaction with Mrg15, and have found that mutation of this motif results in loss of localization of Cap-H2 on polytene chromosomes and results in partial suppression of Cap-H2-mediated compaction and homolog unpairing.