Sentence examples for binding motif while the from inspiring English sources

The N domain contains a classical winged helix-turn-helix (wHTH) DNA binding motif, while the C domain shows a typical restriction endonuclease fold.

The N-terminal region encoded a bZip transcription factor domain with a novel histidine-containing DNA binding motif while the dimerization determinants exhibited two distinct profiles that segregated by class.

The ant algorithm searches for a group of the best motifs in a space of individual binding motifs, while the genetic algorithm seeks the best combination.

The highest sequence similarity within Rho GTPases is found for the central GTP binding motifs while the C-terminal sequences are more divergent [ 12]. Figure 1 gives an overview of the structural elements important for signalling for RhoA, Rac1, Cdc42 as well as RhoH.

All together, these studies suggest that TRF2 promotes t-loops by binding through more than one DNA binding motif while oligomerizing and altering DNA topology through its TRFH domain.

However, recent researches imply that the commonly used product-multinomial model may be too simplistic in identifying the binding motifs, while some positions of TF binding motif exert an interdependent effect on binding affinities of TFs [ 17– 17].

PWMs have their utility as a concise and easy representation of binding motifs, while DWMs offer much better precision in prediction.

Four of the eight SNPs were located in sequences with high homology to transcription factor binding motifs, while SNP -4038 and -2604 were suggested to form new binding sites (Figure 1E).

Of note, the CHR sequence may be aligned with one of the iPLA2 CaM-binding motif (iPLA2618 635), while the CAT sequence aligns with another, i.e. the iPLA2 CaM-binding motif (iPLA2691 709) [41].

Of particular interest was the finding that while the Cts6 binding motif overlaps the NsiI site, the motif would be restored in the four-base (TGCA) deletion.

From our perspective, TF ChIP-Seq data is effectively bi-partite: a subset of ChIP'd regions have a direct relationship to the ChIP'd TF made evident by the presence of the TF's binding motif near the peak local maximum, while the remaining subset of regions are lacking the motif.