Sentence examples for binding motif that can from inspiring English sources
This position also falls within a dileucine binding motif that can bind AP-2 and substitutions here could reduce both AP-2 binding and CD4 downregulation [54].
This places a bound on the relevant length of the binding motif that can readily form in a promoter region of length L. Given L ≈ 300, for example, a motif with = 8 and r s = 3 could still allow for spontaneous adaptive site formation.
A number of studies have shown that transposable elements often serve as sources of ready-to-use binding motifs that can help regulate the expression of networks of genes (Cowley and Oakey, 2013; Sundaram et al., 2014).
At the end of this carboxy terminus there is usually a PDZ domain-binding motif that can interact with PDZ domains of TJ scaffolding/adapter proteins including ZO-1, ZO-2 and ZO-3 [ 59, 60].
Here we utilized studies of Arabidopsis in parallel with heterologous expression of START domains in yeast to investigate the hypothesis that START domains are versatile ligand-binding motifs that can modulate transcription factor activity.
In summary, HMGB1 contains domains with lipid A- and polysaccharide-binding motifs that can neutralize LPS-mediated TNF-α release in human PBMCs and in a subclinical endotoxemia mouse model; peptides that cover these binding regions may potentially be used as anti-septic therapeutic agents and contribute the survival rate for pathological condition of LPS-mediated sepsis.
GAPA contains a putative IQ motif that can mediate binding to calmodulin as in IQGAP1, allowing that Ca2+ affects GAPA functions in actin remodeling.
To search for novel peptides and common binding motif that specifically bind to endometriosis.
The W-box is a binding motif that has been identified in WRKY transcription factors.
These motifs predict transcription-factor binding motifs that may control the expression of each cluster.
In particular, both phospho-motif antibodies that can recognize a broad consensus signature sequence phosphorylated by a specific protein kinase, and phospho-motif-binding proteins that can recognize and enrich protein kinase substrates are increasing in use.
