Sentence examples for binding motif for small from inspiring English sources

Hence, the discovery of efficacious MMP inhibitors without strong zinc-binding functional moieties is a very active field of research toward the generation of clinical treatments for those serious conditions.[ 16] Peptide bonds of the protein backbone represent the ubiquitous binding motif for small molecules to modulate a biological target.

In turn, Caspr1 has a small cytoplasmic tail which contains a binding motif for the scaffold protein 4.1B, and this interaction is important for stabilisation of the Caspr1/contactin-1/NF155 complex at the paranode.

KorA carried a binding motif for coenzyme A, and KorB carried binding motifs for Fe-S cluster and thiamine pyrophosphate.

This approach has been successfully applied to determine a binding motif for the chemokine receptor CXCR4.

Motifs cc_08, cc_10 and cc_11 share similarity with the binding motif for the CtrA cell cycle master regulator.

The FHA domain is expected to work as the binding motif for phosphorylated proteins.

Also, proteobacteria lack a distinct binding motif for CysB.

Motif discovery methods are also used to propose a new binding motif for WT1.

A search for NAD+ and NADP+-binding dinucleotide folds within the protein sequence of TcADD, we found conserved putative binding motifs for both.

The TTGGCAAATA motif appears to resemble overlapping binding motifs for NFI, FoxA1 and Oct-1 (Figure 4C).

Fourteen conserved promoter motifs were identified, seven of which shared significant similarity with binding motifs for previously characterized regulators [25].