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This approach has been successfully applied to determine a binding motif for the chemokine receptor CXCR4.
KorA carried a binding motif for coenzyme A, and KorB carried binding motifs for Fe-S cluster and thiamine pyrophosphate.
The binding motif for Rv1474c in the upstream region of acn (Rv1475c -Rv1474c operon was verified by gel-shift assays.
Our results (submitted) plus Shi's observations (Shi et al., 2015) revealed an unexpected contribution of this unique inserting sequence in constituting an extra-ligand binding motif for FadR regulatory protein.
The VP1 G H loop of the foot-and-mouth disease virus (FMDV) contains the primary antigenic site, as well as an Arg-Gly-Asp (RGD) binding motif for the αv-integrin family of cell surface receptors.
The FHA domain is expected to work as the binding motif for phosphorylated proteins.
Interestingly, Prep1 contains a putative binding motif for 4EHP, which may reflect a novel unknown function.
Motifs cc_08, cc_10 and cc_11 share similarity with the binding motif for the CtrA cell cycle master regulator.
There is also a significant lipid metabolism signature, marked by overexpression of lipid metabolizing enzymes and the presence of the binding motif for Srebp1.
The PH domain works as a binding motif for phosphatidylinositol 4,5 biphosphate, and the PRD domain mediates interaction with various proteins containing SH3 domains [14].
The binding motif for Xbp1 is present in CLN1 promoter, and overexpression of Xbp1 can repress the expression of G1 cyclins and lengthen G1.
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