Sentence examples for binding motif are conserved from inspiring English sources

In both CRB-1 and EAT-20, the essential residues of the FERM-binding motif and the PDZ-domain binding motif are conserved in the intracellular region (Klebes and Knust, 2000; Klose et al., 2013).

Phylogenetic analyses of the three ABLIMs showed that the spectrin CH1 binding motif was conserved in all vertebrate ABLIMs but could not be detected in invertebrate ABLIMs proteins.

Of note, the spacing of the cores within the CTCF1 motif was uniquely lost in human, chimpanzee, and gorilla due to the deletion of spacer base 9; otherwise the binding motif is conserved in placental mammals.

The SH3 binding motif is conserved in dsh-1 and dsh-2 orthologs that contain protein sequence C-terminal to the PDZ and/or N-terminal to the DEP domain, but is entirely absent from all mig-5 orthologs.

Again, both the PPPSP motif and PDZ-binding motif are conserved in LRP2 sequences from different species including man, rodents, and chicken (Marzolo and Farfan, 2011).

A basic tenet of comparative genomic approaches for regulon analysis is the assumption that the transcription factor-binding motif is conserved across the species being studied.

Neither CTCF2- nor CTCF3-binding motifs are conserved in non-placental vertebrates (data not shown).

We were therefore interested in determining to what extent the amino acid-binding signature motif is conserved within the zebrafish OlfC receptor family, and by inference whether the OlfC receptors may constitute a family of amino acid receptors.

For example, we looked for characteristic motifs that had remained invariant among human haplotypes such as the integrin-binding RGD motif and asked if this motif was conserved among other species.

This motif is conserved in the ribokinase family enzymes33,34.

Two active site motifs are conserved.