Sentence examples for binding modes and other from inspiring English sources

While this procedure will not work for an arbitrary set of molecules active against a particular target (due to the presence of different scaffolds, binding modes and other confounding effects), it works in this case due to the constraint of our definition of similarity.

To obtain highly selective and potent Cdk4 inhibitors a structure-based design was performed which consisted of lead generation of a new class of Cdk4 inhibitors based on a Cdk4 homology model, and enhancement of Cdk4 selectivity of lead compounds over Cdk1/2 and other kinases based on the binding modes and structural differences between Cdk4 and other kinases.

Analyses of other LARP family members suggest more diverged RNA binding modes and specialization for cytoplasmic mRNA-related functions.

Newly discovered ggTas2r1 agonists, their predicted binding modes and functional data.

10.7554/eLife.08193.016 Figure 4. SSB binding modes and diffusion mechanism.

We refer to this binding difference as distinct binding modes, and suggest that the different transcriptional outcomes are related to the binding modes.

Next we use it to dock and predict the binding modes of other ggTas2r1 agonists that were shown to activate ggTas2r1 in Behrens et al. 20149.

Table 1 was picked out from the top 200 of docking list by analyzing the binding modes, binding affinity and other properties based on clustering analysis, pharmacophore modeling and docking simulation.

These conditions do not distinguish the CaM binding mode and indeed, they could support both cis- and trans-CaM binding.

The first cycle (blue arrows) led to the investigation of the quinine binding mode and, consequently, the identification of the active conformation of the ggTas2r1 binding site.

To obtain an accurate binding mode and affinity data, docking was conducted in the Geom mode of Surfelx-Dock.