Sentence examples for binding models suggest that from inspiring English sources
50 However, 3-dimensional binding models suggest that the long side chain of posaconazole may result in tighter binding affinity.
The importance of the NP-1 levels as well as the differences observed with the two VEGFf binding models suggest that coupling between VEGFR1 and NP-1 is critical to regulation of VEGF-VEGFR2 binding both in the presence or absence of VEGFf.
However, fitting of the data to a specific binding model suggested that subtle differences in the diffusional behaviour existed between the materials.
It was found that the binding isotherm could not be fitted to the simplest binding model, but fitted into a sequential binding model suggesting that the interaction involves non-symmetric binding to the two AnxA2 peptides: one binding site on the dimer needs to be occupied before the second binding event can take place.
Current models suggest that the binding of P300/CBP cofactors to transcription factor activation domains positions histone acetyltransferases near specific nucleosomes in the promoter regions of the target gene.
Current models suggest that the DNA-binding domains of one tail tail module bind adjacently to a single DNA segment in linear filaments, which form at <5 mM Mg2+, or contact separate DNAs or DNA segments in bridged filaments favored at >5 mM Mg2+ (Liu et al., 2010).
Notably, vinculin also binds α-actinin, and molecular dynamics modeling suggests that mechanical force is required to expose the vinculin-binding site on α-actinin.
Previous models suggest that the C-terminus is solely responsible for receptor binding to facilitate interaction of the N-terminus, which promotes activation (Hoare, 2005).
Current models suggest that CRL complexes are controlled by cycles of CRL deneddylation and CAND1 binding.
Earlier models suggest that cohesin's ATPase head domain is only involved in the initial DNA binding step, and that ATP hydrolysis releases the DNA from cohesin.
The binding data best fit to a 2 1 binding model, suggesting two binding modes for S20 on HA.
