Sentence examples for binding models of the from inspiring English sources

The 2D and 3D binding models of the complex 19a/11β-HSD1 were generated using docking simulations.

The binding models of the investigated antagonists indicate the mechanism of binding of the studied compounds to the CCR5 obviously.

Different binding models of the substrate enantiomers to the active site of CRL were investigated by applying a computational protocol based on molecular docking, conformational analysis, and energy minimization procedures.

We constructed binding models of the TFs regulating pattern formation in the early embryonic development of D. melanogaster (Mel) and applied them to the genome of D. pseudoobscura (Pse).

Using a binding model of the lead and public X-ray coordinates of GLO1 enzymes complexed with glutathione analogues, we designed 4- 7-azaindole -substituted 6-phenyl-N-hydroxypyridones.

(B ) Heatmap showing interdependency between bases in the binding model of the Runt family TF lz.

Migration assay results for the antagonistic compounds 1 and 2 and a binding model of the chimeras to CXCR4.

(4) The heat capacity changes (Δ C p °) associated with the binding of the different SAHA analogues to HDAC8 cannot be rationalized in view of the classical hydrophobic binding model of the enzyme ligand complexes.

Kinetic analysis suggests competitive inhibition and the binding model of these compounds can be rationalized using molecular modelling studies.

The binding model of this particular scaffold is similar to that of Flavopiridol (Figure 1A), an experimental drug currently in clinic trials, with an additional hydrogen bond between the N-H group of the lactam and carbonyl group of Leu83.

In addition, the binding models of 34c with ALKWT, ALKL1196M and ALKG1202R provided structural bases for SARs observations.