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The corresponding model (model 2) is then the same as model 1 removing the polygenic effects.
An alternative model in which Atf3 eliminates the ERK1/2 signal (modelled by removing the ERK1/2 signal upon Atf3 binding; Figure 7A) gave a good qualitative fit.
We therefore propose a model in which JMJD2B at ER binding sites removes the repressive histone marks, which may also set up docking sites for enzymes and transcription factors that remodel chromatin or otherwise modify gene-control regions.
Be extra careful when removing the model from the fridge.
Wait for it to heal before removing the binding.
Removing the non-binding guidance would risk "throwing the baby out with the bathwater", he warned.
The following section describes the Hitch Hiker binding model.
High-Priority Bindings Hitch Hiker extends the event-based LooCI binding model described in Section 3.1.
Section 3 introduces the Hitch Hiker-2.0 binding model.
The binding kinetics were analyzed by BIAevaluation software (Biacore) using a 1 1 Langmuir binding model.
We apologise and removed the model from the figure set.
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